A child with intravenous immunoglobulin–resistant Kawasaki disease who responded to intravenous methyl prednisolone

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Use of Corticosteroid in Children with Unresponsiveness to Intravenous Immunoglobulin in Kawasaki Disease

Background Kawasaki Disease (KD) is a vasculitis with multi-organ involvementof unknown etiology; it is the most common cause of pediatric-heart diseases in developed countries. Treatment with Intravenous Immunoglobulin (IVIG) prevents coronary artery lesions; although there are some IVIG-resistant cases, combination therapy with corticosteroids and IVIG is one of the recommendations for treatm...

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Serpiginous choroiditis with atypical presentation treated with intravenous methyl prednisolone.

PURPOSE The purpose of this study is to report a case of atypical serpiginous choroiditis presenting with disc edema and exudative retinal detachment, treated successfully with intravenous methyl prednisolone. METHODS A 45-year-old male patient presented with sudden decrease of vision in his left eye. On examination, left eye showed disc edema, exudative retinal detachment, and active serpigi...

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High incidence of adrenal suppression in children with Kawasaki disease treated with intravenous immunoglobulin plus prednisolone

Combination treatment with intravenous immunoglobulin (IVIG) plus prednisolone, newly designed for children with severe Kawasaki disease (KD), reduces coronary artery abnormalities significantly. As prednisolone is administered for approximately 20 days in this regimen, we examined whether adrenal function of the treated patients is suppressed. A prospective study was performed at one medical i...

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intravenous immunoglobulin resistant kawasaki disease

abstract kawasaki disease is a systemic vasculitis that mainly affects younger children. although the definite cause still remains unknown but the clinical and epidemiologic findings discuss an infectious cause. the prevalence of incomplete kawasaki disease reported 15 to 36.2%, and it is more frequent in the extremes of the age spectrum. non delayed treatment of disease should be initiated bec...

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Recurrent Kawasaki disease resistant to initial treatment with intravenous immunoglobulin.

Kawasaki disease (mucocutaneous lymph node syndrome) is a disease of unknown etiology characterized by vasculitis which may affect the coronary arteries. Young children are most commonly affected although the disease has been described in adults. Kawasaki disease (KD) was first described by Dr Tomisaku Kawasaki in 1967. Since then, more cases have been reported worldwide, the majority being fro...

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ژورنال

عنوان ژورنال: Sri Lanka Journal of Child Health

سال: 2019

ISSN: 2386-110X,1391-5452

DOI: 10.4038/sljch.v48i3.8767